Marcadores biológicos: PCNA e Ki-67 breve revisão
نویسندگان
چکیده
منابع مشابه
Evaluation of proliferating markers Ki-67, PCNA in gastric cancers.
Tumours from 45 patients with advanced gastric cancer were assessed by immunohistochemistry. Tissue sections were fixed in 10% buffered formaldehyde solution, embedded in paraffin and stained immunohistochemically with anti-human Ki-67 and PCNA antibodies. No correlation was found between Ki-67, PCNA protein expression, the age of patients and the localization of tumour. A significant, positive...
متن کاملImmunohistochemical Expression of PCNA and Ki-67 in Periapical Granuloma and Radicular Cyst
Objectives: Periapical Granulomas (PGs) and Radicular Cysts (RCs), as the most common odontogenic lesions have yet unclear pathogenesis. This study was aimed to compare PCNA and Ki-67 expression in PGs and RCs and evaluate their possible relationship with two lesions. Methods: In this cross-sectional descriptive study, twenty PGs and twenty RCs were evaluated immunohistochemically using an a...
متن کاملExpression of PCNA and Ki-67 in posterior uveal melanomas in adults.
The aim of the study was to evaluate the expression of cell proliferation markers (PCNA and Ki-67) in posterior uveal melanomas in adults. Thirty-six enucleated eyes (without prior treatment) were included in histopatological study. A series of 15 cases of spindle cell type melanomas, 12 epithelioid and 9 of a mixed type were assessed, using the immunohistochemical method with monoclonal PCNA a...
متن کاملImmunohistochemical evaluation of Ki-67, PCNA and MCM2 proteins proliferation index (PI) in advanced gastric cancer.
The current study objective was to assess the proliferation indices (PI) of Ki-67, PCNA and MCM2 proteins in advanced gastric cancer and in metastatic lymph node in correlation with certain clinicopathological features and with postoperative survival of patients. The study was conducted in a group of 100 patients with advanced gastric cancers. Involvement of local lymph nodes was present in 36 ...
متن کاملMCM-2, Ki-67 and PCNA protein expressions in pT3G2 colorectal cancer indicated lymph node involvement.
BACKGROUND The rate of cancer cell growth depends on proliferative activity and on the tumor cell death rate. The study objective was to assess the expressions of Ki-67, PCNA and MCM2 in colorectal cancer and to analyze the correlation between the expressions and chosen anatomo-clinical parameters (patient's age, tumor location, lymph node metastases). PATIENTS AND METHODS The study material ...
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ژورنال
عنوان ژورنال: Brazilian Dental Science
سال: 2010
ISSN: 2178-6011
DOI: 10.14295/bds.1999.v2i1.37